By Douglas J. Martin BS, Edward G. Randles PhD, Marina Ramirez-Alvarado PhD (auth.), Morie A. Gertz, S. Vincent Rajkumar (eds.)
An updated reference in this attention-grabbing set of advanced problems, this ebook gains the main complete innovations for diagnosing, classifying, imaging, treating, and handling amyloidosis in a number of organ platforms. worthy to the spectrum of practitioners from citizens to sub-specialists, this e-book is a succinct authoritative textual content written through leaders within the box. The authors supply guideline on all sorts of amyloidosis - together with fundamental amyloidosis (AL), secondary amyloidosis (AA), and familial amyloidosis. With crucial remedy algorithms, Amyloidosis: analysis and remedy is the gold-standard for all hematologists, oncologists, and internists taking care of sufferers with this disease.
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Additional resources for Amyloidosis: Diagnosis and Treatment
In this series the specificity of AFA is 100 and the sensitivity is 93 when three smears were thoroughly examined . This last result comes from a tertiary center which is experienced in AFA and explains why it has good results compared to other studies. It is thus difficult to express general recommendations with these methods. All these methods are efficient when they are used by experienced hands. Liver Biopsy Vascular involvement is constant in amyloidosis and leads to various bleeding manifestations .
CT appearance of AL nodular pulmonary amyloidosis, with multiple bilateral calcified amyloid nodules of variable diameter. Chapter 2 Imaging of Systemic Amyloidosis the interstitium, with reticular opacities, interlobular septal thickening, micronodules, and, less frequently, ground-glass opacification, traction bronchiectasias, and honeycombing at high-resolution CT . Diffuse amyloidosis is sometimes accompanied by mediastinal lymphadenopathy . In β2 -microglobulin amyloidosis, destructive arthropathy, spondylarthropathy, and periarticular cystic bone lesions can be demonstrated by plain X-ray and CT .
Longitudinal myocardial velocity gradient derived from pulsed Doppler tissue imaging in AL amyloidosis: a sensitive indicator of systolic and diastolic dysfunction. J Am Soc Echocardiogr. 2004;17:36–44. 86. Bellavia D, Abraham TP, Pellikka PA, et al. Detection of left ventricular systolic dysfunction in cardiac amyloidosis with strain rate echocardiography. J Am Soc Echocardiogr. 2007;20:1194–202. 87. Palka P, Lange A, Donnelly JE, Scalia G, Burstow DJ, Nihoyannopoulos P. Doppler tissue echocardiographic features of cardiac amyloidosis.